hydrochloride

American  

[hahy-druh-klawr-ahyd, -id, -klohr-] / ˌhaɪ drəˈklɔr aɪd, -ɪd, -ˈkloʊr- /

noun

1. a salt, especially of an alkaloid, formed by the direct union of hydrochloric acid with an organic base that makes the organic constituent more soluble.

---

hydrochloride British  

/ ˌhaɪdrəˈklɔːraɪd /

noun

1. a quaternary salt formed by the addition of hydrochloric acid to an organic base, such as aniline hydrochloride, [C 6 H 5 NH 3 ] ⁺ Cl ^-

---

hydrochloride Scientific  

/ hī′drə-klôr′īd′ /

1. A salt containing the group HCl. Many important drugs are hydrochlorides.

---

Etymology

Origin of hydrochloride

First recorded in 1820–30; hydro- ² + chloride

Example Sentences

It suggests one of the first medications people should be offered is Xonvea, scientifically known as doxylamine succinate and pyridoxine hydrochloride.

From BBC • Dec. 10, 2025

Next, they treated the cloth with hydroxylamine hydrochloride to add amidoxime groups to the polymers.

From Science Daily • Dec. 13, 2023

She gave me prescriptions for estradiol vaginal tablets, lidocaine hydrochloride jelly USP 2%, and OTC hyaluronic acid vaginal moisturizer.

From New York Times • Jan. 31, 2018

Naloxone hydrochloride, approved by the Food and Drug Administration in 1971, has long been carried by rescue personnel and used in emergency rooms.

From Washington Post • Nov. 22, 2015

The aqueous solution precipitates gelatine and aniline hydrochloride; all other tannin reagents give no reaction.

From Synthetic Tannins by Grasser, Georg