digitoxin

American  

[dij-i-tok-sin] / ˌdɪdʒ ɪˈtɒk sɪn /

noun

Pharmacology.

1. a white, crystalline, water-insoluble cardiac glycoside, C 41 H 64 O 13 , or a mixture of cardiac glycosides of which this is the chief constituent, obtained from digitalis and used in the treatment of congestive heart failure.

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digitoxin British  

/ ˌdɪdʒɪˈtɒksɪn /

noun

1. a white toxic bitter-tasting glycoside, extracted from the leaves of the purple foxglove ( Digitalis purpurea ) and used in the treatment of heart failure and some abnormal heart rhythms. Formula: C 41 H 64 O 13

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digitoxin Scientific  

/ dĭj′ĭ-tŏk′sĭn /

1. A highly active glycoside derived from digitalis and prescribed in the treatment of certain cardiac conditions. Chemical formula: C ₄₁ H ₆₄ O ₁₃ .

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Etymology

Origin of digitoxin

First recorded in 1880–85; digi(talis) + toxin

Example Sentences

Foxglove - digitalis - is a source of digitoxin, a glycoside in the drug digitalis, which has been used as a heart stimulant since 1785.

From BBC • Jul. 10, 2023

If a patient is on digitoxin, one of the digitalis products, and then uses barbiturates for a while, his heart-medicine dosage should be checked, and possibly adjusted, twice.

From Time Magazine Archive

But the heart stimulant digitoxin causes breaks, said Buffalo's Dr. Maimon M. Cohen.

From Time Magazine Archive

And in its action on the heart the digitonin dilates the coronary arteries, according to Macht, while the digitoxin acts on the heart muscle.

From Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. by Warfield, Louis Marshall

The tincture contains a fair proportion of both digitalin and digitoxin.

From Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 4 "Diameter" to "Dinarchus" by Various