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cytotoxic
/ ˌsaɪtəʊtɒkˈsɪsɪtɪ; ˌsaɪtəʊˈtɒksɪk /
adjective
- poisonous to living cells: denoting certain drugs used in the treatment of leukaemia and other cancers
Derived Forms
- cytotoxicity, noun
Example Sentences
The fading-down process works as follows: Specific antibodies coupled to a cytotoxic drug recognize all blood cells in the patient's body based on a surface structure.
"These findings have important implications for cancer immunotherapy in general, as they identify a novel and eminently targetable checkpoint against the function of infiltrating cytotoxic T cells in the tumor microenvironment," said Coukos.
Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer.
They found that treatment with Agent Orange and its constituents caused changes in the brain tissue corresponding to brain cell degeneration, and molecular and biochemical abnormalities indicative of cytotoxic injury, DNA damage and other issues.
The scientists had previously discovered that the formation of abnormal or "bad" myelin in these mice leads to an inflammatory reaction comprising an accumulation of cytotoxic CD8+ T cells.
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