imipramine

American  

[ih-mip-ruh-meen] / ɪˈmɪp rəˌmin /

noun

Pharmacology.

1. a tricyclic antidepressant, C 19 H 24 N 2 , used for the symptomatic relief of depression.

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imipramine British  

/ ɪˈmɪprəˌmiːn /

noun

1. a tricyclic antidepressant drug. Formula: C 19 H 24 N 2

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Etymology

Origin of imipramine

1955–60; contraction and rearrangement of iminodibenzyl and aminopropyl, components of the chemical name

Example Sentences

These kinds of symptoms were more common after discontinuing treatment with the drugs imipramine, paroxetine, venlafaxine, and desvenlafaxine.

From Science Daily • Jun. 6, 2024

But he would be dancing at the edge of science to put suicidal patients on Prozac, while patients with melancholic depression may in fact do quite well on older agents such as imipramine.

From Washington Post • Jun. 9, 2016

The new reanalysis revealed that neither Paxil nor high-dose imipramine was more effective than a placebo in the treatment of major depression in adolescents.

From US News • Sep. 16, 2015

The tricyclic antidepressant imipramine was the first to gain popularity; it was later supplanted by desmopressin, which reduces the amount of urine you make while sleeping.

From Slate • Jul. 24, 2015

The other showed that an antidepressant called imipramine, which was known to block NPC1, seemed to prevent infection as well.

From New York Times • Jan. 16, 2012