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C-reactive protein

American  
[see-ree-ak-tiv] / ˈsi riˌæk tɪv /

noun

Biochemistry.
  1. a globulin that increases in concentration in the bloodstream during infectious states and other abnormal conditions. CRP


C-reactive protein Scientific  
/ sērē-ăk′tĭv /
  1. An antibody found in the blood in certain acute and chronic conditions including infections and cancers. It is a nonspecific indicator of inflammation and therefore not diagnostic of any one disease.


Etymology

Origin of C-reactive protein

First recorded in 1955–60; for C-polysaccharide, which is precipitated by this protein

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Blood samples were also analyzed for high-sensitivity C-reactive protein, a widely used marker of inflammation.

From Science Daily • Mar. 19, 2026

C-reactive protein, a liver product that’s linked to inflammation, fell about 40% among those taking Wegovy.

From Seattle Times • Nov. 11, 2023

The results demonstrated improvements in many variables related to cardio-metabolic health, such as blood cholesterol, blood pressure, insulin and C-reactive protein — a protein that increases in response to inflammation.

From Salon • Oct. 3, 2021

Gum-disease bacteria may travel to the liver and raise levels of C-reactive protein, which is an indicator of inflammation involved in many conditions, including heart disease and Type 2 diabetes.

From Washington Post • Sep. 30, 2016

C-reactive protein is induced to be made by the liver and will opsonize certain species of bacteria.

From Textbooks • Jun. 19, 2013