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Benadryl

American  
[ben-uh-dril] / ˈbɛn ə drɪl /
Pharmacology, Trademark.
  1. a brand of diphenhydramine.


Benadryl British  
/ ˈbɛnədrɪl /

noun

  1. an antihistamine drug used in sleeping tablets; diphenhydramine. Formula: C 17 H 21 NO

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Sales rose 1.5% in Kenvue’s self care business, which includes products such as Tylenol and Benadryl.

From The Wall Street Journal • Feb. 17, 2026

If you’re highly allergic to mosquitoes, he said, you may need a cream with Benadryl or similar antihistamine.

From Los Angeles Times • Feb. 14, 2024

Classic brand names like Benadryl, Claritin, Allegra, and Zyrtec are antihistamines, which can be used to treat, or lessen, that histamine reaction and thus the itch.

From Slate • Sep. 23, 2023

If the F.D.A. ordered their removal, a trade group warned that numerous popular products — including Tylenol, Mucinex and Benadryl cold and flu remedies — might become unavailable as companies race to reformulate them.

From New York Times • Sep. 12, 2023

She’s wearing a pink shirt and holding a bottle of pink Benadryl.

From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot