prolongation

[ proh-lawng-gey-shuhn, -long- ]

noun

1. the act of prolonging:

   the prolongation of a line.

2. the state of being prolonged.
3. a prolonged or extended form.
4. an added part.

Other Words From

• nonpro·lon·gation noun

Word History and Origins

Origin of prolongation¹

1480–90; < Late Latin prōlongātiōn- (stem of prōlongātiō ) extension. See prolongate, -ion

Example Sentences

In the past, intermittent fasting has been shown to prolong the lifespan of animals, and the results now obtained indicate that the improved preservation of stem cell function may underlie this prolongation.

From Science Daily

Lead investigator of the study Shang-Hung Chang, MD, PhD, of the Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, adds, "The use of the antipsychotics quetiapine and haloperidol to treat mental disorders is widespread. In an effort to enhance patient safety and optimize the management of individuals receiving these medications, we have investigated the incidences, risk factors, and clinical outcomes of severe QT prolongation to provide valuable insights for healthcare professionals, patients, and caregivers."

From Science Daily

The most significant results of the study were that more than 10% of patients developed severe QT prolongation during follow-up and the increased risk of ventricular arrhythmias and sudden cardiac death in quetiapine or haloperidol users who developed severe QT prolongation.

From Science Daily

"Clinicians should be aware of the potential risks associated with quetiapine use, particularly the risk of severe QT prolongation and its associated outcomes, including ventricular arrhythmias and sudden cardiac death."

From Science Daily

Professor Vandenberg comments, "It would be prudent to undertake an ECG before and after commencement of an antipsychotic drug. If it is an option, one could stop a drug causing QT prolongation and try a different antipsychotic. But if this is not practical, one should pay particular attention to reducing other risk factors, such as prescription of other drugs that may exacerbate QT prolongation and be vigilant for hypokalemia."

From Science Daily

Related Words

• continuation