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HLA

American

Immunology.

human leukocyte antigen: any of a complex of genetically determined antigens, occurring on the surface of almost every human cell, by which one person's cells can be distinguished from another's and the histocompatibility and genetic likeness of any two persons can be established: the major histocompatibility antigen of humans.

Etymology

Origin of HLA

First recorded in 1965–70

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Ashouri would work to ensure that L.A. complies with Measure HLA, the 2024 ballot measure that requires the installation of bus or bike lanes during major road repairs.

From Los Angeles Times • May 1, 2026

Their experiments showed that removing surface proteins known as HLA class 1 molecules allowed NK cells to avoid attack from T cells in the host’s immune system.

From Science Daily • Oct. 11, 2025

But the scope of Measure HLA — the citywide initiative to follow through on what L.A.

From Los Angeles Times • Apr. 3, 2025

“However, HLA does not apply to Metro projects.”

From Los Angeles Times • Apr. 3, 2025

By testing Henrietta’s children, they hoped to find out what Henrietta’s HLA markers might have been, so they could use those to identify her cells.

From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023