IgG

American  

Immunology.

1. immunoglobulin G: a class of circulating antibodies predominant in serum, produced by plasma cells and memory cells in response to pathogens and other foreign substances, able to pass through the placental wall to the fetal circulation to impart immune defense for the period of infancy.

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Etymology

Origin of IgG

First recorded in 1960–65

Example Sentences

The research team first modified the antibody by altering the IgG DNA sequence to "give it a different backbone" that converted it into a dIgA antibody.

From Science Daily • Nov. 19, 2025

None of these differences, like IgG which is also in human breast milk, is necessarily harmful to humans.

From Salon • Jan. 19, 2024

To overcome this, the group led by professor Qiang Pan-Hammarström at Karolinska Institutet used genetic engineering to create IgA antibodies that bind to the SARS-CoV-2 spike protein in a similar way to the IgG antibodies.

From Science Daily • Jan. 10, 2024

As the primary response proceeds, the antibody produced in a B cell can change to IgG, IgA, or IgE by the process known as class switching.

From Textbooks • Jun. 19, 2013

If the mother has a second Rh-positive child, IgG antibodies against Rh-positive blood mounted during this secondary response cross the placenta and attack the fetal blood, causing anemia.

From Textbooks • Jun. 19, 2013