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IgG

American

Immunology.

immunoglobulin G: a class of circulating antibodies predominant in serum, produced by plasma cells and memory cells in response to pathogens and other foreign substances, able to pass through the placental wall to the fetal circulation to impart immune defense for the period of infancy.

Etymology

Origin of IgG

First recorded in 1960–65

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Laboratory analyses showed strong IgG responses and neutralizing antibodies against SARS-CoV-2, along with immune-related proteins and metabolites linked to early host defense.

From Science Daily • Jan. 8, 2026

To confirm that these glycan-associated disruptions were causal rather than merely correlative, the research team engineered HIV-specific antibodies designed to exhibit the same kind of aberrant IgG glycan modifications observed in PLWH.

From Science Daily • Apr. 10, 2024

None of these differences, like IgG which is also in human breast milk, is necessarily harmful to humans.

From Salon • Jan. 19, 2024

The total number of IgA molecules in these bodily secretions is greater than the number of IgG molecules in the blood serum.

From Textbooks • Jun. 9, 2022

If the mother has a second Rh-positive child, IgG antibodies against Rh-positive blood mounted during this secondary response cross the placenta and attack the fetal blood, causing anemia.

From Textbooks • Jun. 19, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023