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cytoplasm

American  
[sahy-tuh-plaz-uhm] / ˈsaɪ təˌplæz əm /

noun

Cell Biology.
  1. the cell substance between the cell membrane and the nucleus, containing the cytosol, organelles, cytoskeleton, and various particles.


cytoplasm British  
/ ˈsaɪtəʊˌplæzəm /

noun

  1. the protoplasm of a cell contained within the cell membrane but excluding the nucleus: contains organelles, vesicles, and other inclusions

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cytoplasm Scientific  
/ sītə-plăz′əm /
  1. The jellylike material that makes up much of a cell inside the cell membrane, and, in eukaryotic cells, surrounds the nucleus. The organelles of eukaryotic cells, such as mitochondria, the endoplasmic reticulum, and (in green plants) chloroplasts, are contained in the cytoplasm. The cytoplasm and the nucleus make up the cell's protoplasm.

  2. See more at cell


cytoplasm Cultural  
  1. The material within a biological cell that is not contained in the nucleus or other organelles.


Other Word Forms

  • cytoplasmic adjective
  • cytoplasmically adverb

Etymology

Origin of cytoplasm

First recorded in 1870–75; cyto- + -plasm

Compare meaning

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Explanation

The human body is made up of cells, and within every cell is a nucleus — everything else contained within the cell walls is the cytoplasm. This is one of many technical terms for the little building blocks of life within us all. Cytoplasm consists of all the substances within the cell walls but outside of the nucleus: a fluid called cytosol, organelles such as the mitochondria, and tiny particles in suspension called inclusions. Cytoplasm is full of proteins, which are essential to your body. Cytoplasm is also called protoplasm. To see cytoplasm, you'll need a good microscope. To understand cytoplasm, you'll need a good biology teacher.

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Vocabulary lists containing cytoplasm

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Meanwhile, ParM does not form structures in the cytoplasm to move DNA.

From Science Daily • Apr. 20, 2026

They discovered that the cytoplasm becomes stiffer during interphase, creating a supportive scaffold that stabilizes the actin band.

From Science Daily • Feb. 28, 2026

Because microtubules can influence how stiff the cytoplasm is, the researchers asked whether asters might help anchor the actin band by stiffening the cell interior.

From Science Daily • Feb. 28, 2026

After DNA separation, large microtubule structures called asters expand throughout the cytoplasm.

From Science Daily • Feb. 28, 2026

After the first, preliminary steps of oxidation have been performed in the cytoplasm the fuel molecule is taken into the mitochondria.

From "Silent Spring" by Rachel Carson