ATPase

American  

[ey-tee-pee-eys, -eyz] / ˈeɪˈtiˈpi eɪs, -eɪz /

noun

Biochemistry.

1. adenosine triphosphatase: any of several enzymes that catalyze the hydrolysis of ATP to ADP and phosphate.

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ATPase British  

/ ˌeɪtiːˈpiːˌeɪz /

noun

1. adenosine triphosphatase; an enzyme that converts ATP to ADP

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Etymology

Origin of ATPase

First recorded in 1945–50; ATP + -ase

Example Sentences

Medications such as omeprazole, pantoprazole, and esomeprazole work by blocking the H+, K+, ATPase enzyme, also known as the proton pump.

From Science Daily • Feb. 26, 2026

Specifically, when ingested, the toxin targets the electrolyte pumps in the wall of the heart called the sodium potassium ATPase pump.

From Salon • Apr. 10, 2025

Rapid restoration of cytoplasmic pH does not occur in the presence of ATPase inhibitors.

From Textbooks • Jun. 9, 2022

The Na+/K+ ATPase pumps in the basal membrane create an electrochemical gradient, allowing reabsorption of Cl– by Na+/Cl– symporters in the apical membrane.

From Textbooks • Jun. 19, 2013

The PCT is the most metabolically active part of the nephron and uses a wide array of protein micromachines to maintain homeostasis—symporters, antiporters, and ATPase active transporters—in conjunction with diffusion, both simple and facilitated.

From Textbooks • Jun. 19, 2013