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ATPase

American

[ey-tee-pee-eys, -eyz] / ˈeɪˈtiˈpi eɪs, -eɪz /

noun

Biochemistry.

adenosine triphosphatase: any of several enzymes that catalyze the hydrolysis of ATP to ADP and phosphate.

ATPase British

/ ˌeɪtiːˈpiːˌeɪz /

noun

adenosine triphosphatase; an enzyme that converts ATP to ADP

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of ATPase

First recorded in 1945–50; ATP + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Medications such as omeprazole, pantoprazole, and esomeprazole work by blocking the H+, K+, ATPase enzyme, also known as the proton pump.

From Science Daily • Feb. 26, 2026

Specifically, when ingested, the toxin targets the electrolyte pumps in the wall of the heart called the sodium potassium ATPase pump.

From Salon • Apr. 10, 2025

The Na+-K+ ATPase exists in two forms, depending on its orientation to the interior or exterior of the cell and its affinity for either sodium or potassium ions.

From Textbooks • Jun. 9, 2022

The Na+/K+ ATPase pumps in the basal membrane create an electrochemical gradient, allowing reabsorption of Cl– by Na+/Cl– symporters in the apical membrane.

From Textbooks • Jun. 19, 2013

Aldosterone stimulates principal cells to manufacture luminal Na+ and K+ channels as well as Na+/K+ ATPase pumps on the basal membrane of the cells.

From Textbooks • Jun. 19, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023