dehydrogenase

American  

[dee-hahy-druh-juh-neys, -neyz] / diˈhaɪ drə dʒəˌneɪs, -ˌneɪz /

noun

Biochemistry.

1. an oxidoreductase enzyme that catalyzes the removal of hydrogen.

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dehydrogenase British  

/ diːˈhaɪdrədʒəˌneɪz /

noun

1. an enzyme, such as any of the respiratory enzymes, that activates oxidation-reduction reactions by transferring hydrogen from substrate to acceptor

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Etymology

Origin of dehydrogenase

First recorded in 1920–25; dehydrogen(ate) + -ase

Example Sentences

Fomepizole works by blocking enzymes known as alcohol dehydrogenase, stopping the body from converting ethylene glycol and methanol into toxic byproducts.

From Science Daily • Jan. 18, 2026

Within the standard therapy group, the researchers discovered that patients who had a high tumor burden or elevated levels of the enzyme lactate dehydrogenase had shorter event-free survival.

From Science Daily • Jan. 17, 2024

"We show in this study that CD8+ T cells indeed engage this metabolic pathway, and that an extensively characterized metabolic enzyme known as isocitrate dehydrogenase plays a central role in the process," said Ho.

From Science Daily • Sep. 20, 2023

Pyruvate dehydrogenase is also regulated by phosphorylation: A kinase phosphorylates it to form an inactive enzyme, and a phosphatase reactivates it.

From Textbooks • Jun. 9, 2022

If more energy is needed, more pyruvate will be converted into acetyl CoA through the action of pyruvate dehydrogenase.

From Textbooks • Jun. 9, 2022