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transcriptome
/ trænˈskrɪptəʊm /
noun
- biochem a collection of all the messenger RNA in a particular cell
Example Sentences
Here, the researchers were able to leverage new third-generation long-read sequencing technologies to capture complete RNA molecules and profile the full-length transcriptome of two major regions of the developing neocortex: the germinal zone, which contains stem cells, and the cortical plate, which houses newly generated neurons.
RNA is produced when cells translate the information of their genes into proteins -- a so-called transcriptome analysis can reveal the current state and characteristics of a cell.
By comparing their newly sequenced cattle horn transcriptome to deer antler and pig skin transcriptomes, Calamari and Flynn confirmed for the first time with transcriptomes that family-specific differences in headgear likely evolved as elaborations on a general bony structure inherited from a common ancestor.
Through an examination of the transcriptome of hESCs cultivated under different cell densities, the researchers pinpointed a key player known as "ETV4," responsible for mediating variations in stem cell density and controlling differentiation.
The researchers looked at whole transcriptome sequencing data of 1,532 pediatric tumor samples with 7,460 normal tissue samples, finding which exons were more highly selective or uniquely expressed in cancer cells than normal cells.
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