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tetramer
[ te-truh-mer ]
noun
- a molecule composed of four identical, simpler molecules.
- a polymer derived from four identical monomers.
Example Sentences
These mutations, which prevent the p53 protein from forming a tetramer -- an assembly of four p53 proteins -- had been studied before, using a technique that involves inserting artificial copies of a mutated p53 gene into a cell.
However, when the MIT team introduced those same mutations using the new prime editing technique, they found that the mutation prevented the tetramer from forming, allowing the cells to survive.
Each nucleosome consists of approximately 147 base pairs of DNA wrapped around a histone octamer which is composed of two H2A-H2B dimers and one H3-H4 tetramer.
Further analysis using X-ray crystallography and thermodynamic simulations revealed that tetramer formation is driven by hydrophobic interactions occurring between two 3D-DS dimers.
The formation of the 3D-DS tetramer can help prevent protein aggregation by decreasing flexibility, potentially avoiding the formation of insoluble aggregates.
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