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radioimmunoassay
[ rey-dee-oh-im-yuh-noh-as-ey, -a-sey, -i-myoo- ]
noun
- a test procedure that integrates immunologic and radiolabeling techniques to measure minute quantities of a substance, as a protein, hormone, or drug, in a given sample of body fluid or tissue.
radioimmunoassay
/ ˈreɪdɪəʊˌɪmjʊnəʊˈæseɪ /
noun
- a sensitive immunological assay, making use of antibodies and radioactive labelling, for the detection and quantification of biologically important substances, such as hormone concentrations in the blood
radioimmunoassay
/ rā′dē-ō-ĭm′yə-nō-ăs′ā,-ĭm-yo̅o̅′- /
- An immunoassay in which the substance to be identified or quantified is labelled with a radioactive substance (called a tracer ), such as an ion.
- See also immunoassay
Word History and Origins
Origin of radioimmunoassay1
Example Sentences
Many of the private testing labs hired by manufacturers seeking regulatory approval for new products are not equipped to do the radioimmunoassay analyses required to measure extremely low chemical concentrations.
But a few drops of blood from a pinprick on the newborn’s heel can be analyzed with radioimmunoassay to identify babies at risk.
In their work on radioimmunoassay, Dr. Yalow and Dr. Berson used radioactive tracers to measure hormones that were otherwise difficult or impossible to detect because they occur in extremely low concentrations.
Scientific journals initially refused to publish their discovery of insulin antibodies, a finding fundamental to radioimmunoassay.
Using radioimmunoassay, she determined that people with Type 2 diabetes produced more insulin than non-diabetics, providing early evidence that an inability to use insulin caused diabetes.
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