pyrimethamine

[ pahy-ruh-meth-uh-meen, -min ]

noun

, Pharmacology.

1. a potent substance, C 1 2 H 1 3 ClN 4 , used against susceptible plasmodia in the prophylactic treatment of malaria and against Toxoplasma gondi in the treatment of toxoplasmosis.

Word History and Origins

Origin of pyrimethamine¹

First recorded in 1950–55; pyrim(idine) + eth(yl) + -amine

Example Sentences

They also argued that other companies had been able to buy the key ingredient, pyrimethamine, contradicting an FTC allegation.

From Reuters

This drug was then changed to sulfadoxine/pyrimethamine in the early 2000’s and resistance occurred.

From Scientific American

In 2012, the World Health Organization recommended the strategy with three old drugs — sulphadoxine, pyrimethamine and amodiaquine — so that the only sure-fire cure for malaria, artemisinin, would remain effective.

From Nature

Pyrimethamine is used to treat the parasitic diseases toxoplasmosis and isosporiasis.

From Nature

Participants received pyrimethamine for nine months.

From Nature