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prothrombin

[ proh-throm-bin ]

noun

, Biochemistry.
  1. a plasma protein involved in blood coagulation that on activation by factors in the plasma is converted to thrombin.


prothrombin

/ prəʊˈθrɒmbɪn /

noun

  1. biochem a zymogen found in blood that gives rise to thrombin on activation See also phylloquinone
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

prothrombin

/ prō-thrŏmbĭn /

  1. A glycoprotein that is converted to thrombin during blood clotting. Prothrombin is formed by and stored in the liver.
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Word History and Origins

Origin of prothrombin1

First recorded in 1895–1900; pro- 1 + thrombin
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Example Sentences

They found I have a blood disorder called prothrombin gene mutation.

I had barely removed my coat before the doctor started rattling off the things I had tested negative for: antiphospholipid antibodies, lupus anticoagulant, Factor V Leiden, prothrombin gene mutation.

This is a difficult drug to control, and close monitoring of prothrombin times — a measure of how long it takes a person’s blood to clot — is necessary.

Wrong prothrombin time results could cause doctors to prescribe too little or too much warfarin.

Tests showed that she has a prothrombin gene mutation that, with estrogen, is a time bomb.

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