proteoglycan

[ proh-tee-oh-glahy-kan ]

noun

, Biochemistry.

1. a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue.

Word History and Origins

Origin of proteoglycan¹

1969; prote(in) + -o- + glyc- + -an, variant of -ane

Example Sentences

They noticed one protein, called proteoglycan glypican-1, was found in much higher levels in people with pancreatic cancer.

From BBC

Our results identify a regulatory axis controlled by a conserved microRNA that maintains proteoglycan homeostasis in cells.

From Science Magazine

The results suggest that proteoglycan biosynthesis is tightly regulated by a microRNA pathway to shape the cell surface glycosylation architecture required to direct neuronal migration.

From Science Magazine

Goblet cells produce mucin, that is organized into a dense, more highly cross-linked inner proteoglycan gel that forms an IEC-adherent inner mucous layer, and a less densely cross-linked outer mucous layer.

From Nature

Goblet cells produce mucin, that is organized into a dense, more highly cross-linked inner proteoglycan gel that forms an IEC-adherent inner mucous layer, and a less densely cross-linked outer mucous layer.

From Nature