plasminogen

[ plaz-min-uh-juhn, -jen ]

noun

, Biochemistry.

1. the blood substance that when activated forms plasmin.

plasminogen

/ plæzˈmɪnədʒən /

noun

1. biochem a zymogen found in blood that gives rise to plasmin on activation

Word History and Origins

Origin of plasminogen¹

First recorded in 1940–45; plasmin + -o- + -gen

Example Sentences

And scientists at Beth Israel Deaconess Medical Center have begun enrolment for a clinical trial to evaluate an even more powerful clot-busting medication called tissue plasminogen activator, or tPA.

From Nature

In New York, Poor was going a step further with a drug called tissue plasminogen activator, or tPA, which doesn’t prevent clots — it breaks them up.

From Los Angeles Times

Physicians have effective methods of clearing these occlusions: clot-busting proteins called tissue plasminogen activators and thrombectomy, a surgical technique.

From Scientific American

Until recently the only treatment available for ischemic stroke was tissue plasminogen activator, or tPA, a protein that can dissolve blood clots if injected up to four and a half hours after stroke onset.

From Scientific American

One treatment is the clot buster tPA — a tissue plasminogen activator — which requires an IV and must be administered within 4½ hours of the stroke occurring.

From Washington Post