nucleoside

[ noo-klee-uh-sahyd, nyoo- ]

noun

, Biochemistry.

1. any of the class of compounds derived by the hydrolysis of nucleic acids or nucleotides, consisting typically of deoxyribose or ribose combined with adenine, guanine, cytosine, uracil, or thymine.

nucleoside

/ ˈnjuːklɪəˌsaɪd /

noun

1. biochem a compound containing a purine or pyrimidine base linked to a sugar (usually ribose or deoxyribose)

nucleoside

/ no̅o̅′klē-ə-sīd′ /

1. Any of various compounds consisting of a sugar, usually ribose or deoxyribose, and a nitrogen base (a purine or pyrimidine). Nucleosides are constituents of the nucleotides of nucleic acids. Adenosine and thymidine are nucleosides.

Word History and Origins

Origin of nucleoside¹

First recorded in 1910–15; nucle(o) ( def ) + -ose ² + -ide ( def )

Word History and Origins

Origin of nucleoside¹

C20: from nucleo- + -ose ² + -ide

Example Sentences

Since the early days of the COVID-19 pandemic, researchers have been working on an oral antiviral drug of the parent nucleoside of remdesivir that could stop replication of the virus.

From Science Daily

The two laureates jointly developed so-called nucleoside base modifications, which stop the immune system from launching an inflammatory attack against lab-made mRNA, previously seen as a major hurdle against any therapeutic use of the technology.

From Reuters

She wanted to raise money to try to fly to Canada for an experimental nucleoside therapy which she thought might help her rare genetic disorder.

From BBC

ST believes she can stay alive for long enough to go for experimental nucleoside therapy treatment abroad, despite there being no centre offering it to her yet and no guarantee it would help her.

From BBC

There, Elisa Biondi, a molecular biologist, and her colleagues ground each sample into a fine powder, sterilized it, and mixed it with a solution of nucleoside triphosphates.

From Science Magazine