nucleolar

[ noo-klee-uh-ler, nyoo-, noo-klee-oh-, nyoo- ]

adjective

, Cell Biology.

1. of, relating to, or forming a nucleolus.

Other Words From

• multi·nu·cleo·lar adjective

Word History and Origins

Origin of nucleolar¹

First recorded in 1860–65; nucleol(us) + -ar ¹

Example Sentences

Impairment of ribosome production and other nucleolar dysfunctions lie at the heart of cancers, neurodegeneration and developmental disorders.

From Science Daily

In a first for the condensate field, researchers from the lab of Rohit Pappu, the Gene K. Beare Distinguished Professor of biomedical engineering, and colleagues in the Center for Biomolecular Condensates in the McKelvey School of Engineering at Washington University in St. Louis, figured out how nucleolar sub-structures are assembled.

From Science Daily

Building on spatial proteomics data from the lab of Emma Lundberg, associate professor of bioengineering at Stanford University, and novel algorithms developed by Kiersten Ruff, a staff research scientist at McKelvey, and colleagues in the Pappu lab, the team identified unique "molecular grammars" including the presence of proteins with long acidic tracts as a key defining feature of many nucleolar proteins.

From Science Daily

Nucleolar nucleolin has a role in chromatin remodeling and gene transcription, and interestingly enough, Wnt pathway genes were differentially expressed in the RNA-seq data following iSN04 suppression.

From Science Daily

DSS cross-links for the nucleolar pre-60S ribosomal subunit.

From Nature