neurotoxicity

[ noor-oh-tok-sis-i-tee, nyoor- ]

noun

1. the degree to which a substance is poisonous to nerve tissue.
2. Pathology. the condition resulting from exposure to a neurotoxin.

Word History and Origins

Origin of neurotoxicity¹

First recorded in 1945–50; neuro- + toxicity

Example Sentences

According to the study, health concerns related to flame retardants include “carcinogenicity, endocrine disruption, neurotoxicity, and reproductive and developmental toxicity.”

From Salon

Grandjean added that "public authorities have prevailed for decades in recommending fluoride intake from drinking water, despite the increasing evidence that fluoride is toxic to the brain. With the advent of fluoridated toothpaste, other countries without fluoride in the drinking water have similar caries occurrence as the U.S. So the dental health advantage of fluoride addition is, at best, minimal and certainly questionable and cannot overrule the well-documented neurotoxicity."

From Salon

At higher levels, they observed a progressive degeneration of the nerve and increased neurotoxicity due to excess inflammation.

From Science Daily

In preliminary in vitro and mouse-model experiments, the polymer-modified trastuzumab did not induce neurotoxicity, did not show adverse effects in the liver, and did not disrupt the integrity of the blood-brain barrier.

From Science Daily

The drug was found to be safe, with manageable side effects, including cytokine-release syndrome in four patients and immune-cell-related neurotoxicity syndrome in three patients.

From Science Daily