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mutagenesis

[ myoo-tuh-jen-uh-sis ]

noun

  1. the origin and development of a mutation.


mutagenesis

/ ˌmjuːtəˈdʒɛnɪsɪs /

noun

  1. genetics the generation, usually intentional, of mutations
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Other Words From

  • mu·ta·ge·net·ic [myoo-t, uh, -j, uh, -, net, -ik], adjective
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Word History and Origins

Origin of mutagenesis1

From New Latin, dating back to 1950–55; mutation, -genesis
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Word History and Origins

Origin of mutagenesis1

C20: from mutation + -genesis
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Example Sentences

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and synthesis.

The paper, "Base editing mutagenesis maps functional alleles to tune human T cell activity," was published in Nature on December 13.

"Xiangyu's comprehensive study of the structure highlights the advantage that a targeted, structurally guided approach has over large and costly random mutagenesis screening."

“That is what we term lethal mutagenesis,” he adds.

The use of this technique could be seen as a weakness of Wang and co-workers’ approach, because unnatural-amino-acid mutagenesis is not suitable for all cell types, and can require substantial optimization for each application.

From Nature

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mutagenmutagenic