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morpholino

/ ˌmɔːfəʊˈliːnəʊ /

noun

  1. a type of molecule used in altering the development of genes by preventing the access of other molecules
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


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Word History and Origins

Origin of morpholino1

C21: from the organic compound morpholine
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Example Sentences

An additional trawl through genetic databases and the morpholino literature revealed that 80% of results from published morpholino experiments were not reproducible in genetic mutants2.

From Nature

Using this animal model, we have developed an antisense morpholino–based therapy that prevents the pathogenic Lmna splicing, markedly reducing the accumulation of progerin and its associated nuclear defects.

Writing in the journal Nature Medicine, Sina Bavari and colleagues said the drugs tested are antisense phosphorodiamidate morpholino oligomers, or PMOs, called AVI-6002 and AVI-6003.

From Reuters

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morpholinemorphologic construction