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monovalent

[ mon-uh-vey-luhnt ]

adjective

  1. Chemistry. univalent.
  2. Immunology.
    1. containing only one kind of antibody.
    2. pertaining to an antibody fragment with one antigen-binding site.


monovalent

/ ˌmɒnəʊˈveɪlənt /

adjective

  1. chem Alsounivalent
    1. having a valency of one
    2. having only one valency
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


monovalent

/ mŏn′ə-vālənt /

  1. Having a valence of 1; univalent.
  2. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.


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Derived Forms

  • ˌmonoˈvalence, noun
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Other Words From

  • mono·valence mono·valen·cy noun
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Word History and Origins

Origin of monovalent1

First recorded in 1865–70; mono- + -valent
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Example Sentences

Some countries were indeed able to quash type 2 outbreaks with the monovalent vaccine.

They found that the monovalent vaccine increased their ability to produce mucosal antibodies against most of the tested variants, whereas the bivalent vaccine didn't provide a significant boost.

Tan, chief policy and partnerships officer at Immunize.org, told Salon he thinks it's difficult to make a definitive statement that the bivalent boosters weren't as effective as the monovalent ones.

From Salon

It has found that monovalent vaccines against Omicron perform somewhat better than those that include the ancestral strain.

Likewise, FDA spokeswoman Abby Capobianco said that such claims tying the discontinuation of the monovalent shots to safety “are entirely false and without basis in fact.”

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