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mild cognitive impairment
[ mahyld kog-ni-tiv im-pair-muhnt ]
noun
- a stage of cognitive decline, characterized by certain diminished mental abilities, as memory and concentration, but not to an extent that affects daily functioning. : MCI
Word History and Origins
Origin of mild cognitive impairment1
Example Sentences
The company presented its final report on the pivotal studies examining aduhelm’s effectiveness—the ones behind the drug’s approval—in people with mild cognitive impairment or mild Alzheimer’s dementia.
The companies conducted two similar studies, started several months apart, focusing on patients with mild cognitive impairment and evidence of amyloid in the brain, as confirmed by brain imaging.
The FDA said Thursday in a statement that “it was important to clarify the intent” of the label — specifically, that any initiation of Aduhelm should occur in patients in the mild cognitive impairment or early dementia stages of Alzheimer’s.
As a practical matter, doctors and insurers will be left to decide whether to restrict the drug to the population studied in the clinical trials — people with mild cognitive impairment and early dementia, both caused by Alzheimer’s.
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