metoclopramide

[ met-oh-kloh-pruh-mahyd ]

noun

, Pharmacology.

1. a white crystalline substance, C 1 4 H 2 2 ClN 3 O 2 , used primarily in the symptomatic treatment of certain upper gastrointestinal tract problems, and as an antiemetic.

Word History and Origins

Origin of metoclopramide¹

met(h)o(benzamide) a component + c(h)lo(ro)- ² + -pr- of uncertain derivation + amide

Example Sentences

Patients taking certain drugs for acid reflux and other stomach disorders, such as metoclopramide, also have developed tardive dyskinesia.

From Seattle Times

The results of the mid-stage study, published in a medical journal, tested the drug, metoclopramide, in 89 diabetic gastroparesis patients dosed four times a day for 6 weeks.

From Reuters

In 2009, the Food and Drug Administration required all manufacturers of metoclopramide, the generic name for Reglan, to place stronger warnings on their labels detailing a link between long-term use of the drug and tardive dyskinesia.

From New York Times

The decision considered three consolidated cases brought by women who took generic metoclopramide, which is sold under the brand name Reglan.

From New York Times

“If they had done so,” Justice Thomas wrote of a possible request for a label change, “and if the F.D.A. decided there was sufficient supporting information, and if the F.D.A. undertook negotiations with the brand-name manufacturer, and if adequate label changes were decided on and implemented, then the manufacturers would have started a Mouse Trap game that eventually led to a better label on generic metoclopramide.”

From New York Times