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medulloblastoma
/ mɪˌdʌləʊblæsˈtəʊmə /
noun
- a rapidly growing brain tumour that develops in children and is responsive to radiotherapy
Example Sentences
In addition to diseases characterized by bone loss, Ctdnep1 has also been reported as a causative factor in medulloblastoma -- a childhood brain tumor.
Medulloblastoma are the most common type of malignant brain cancer in children.
The most aggressive and difficult-to-treat form of the disease is group 3 medulloblastoma, which is often fatal.
By targeting long, noncoding genetic material called lnc-RNAs that drive the expression of cancer-causing genes, the study's senior author, Ranjan Perera, Ph.D., director of the Center for RNA Biology at Johns Hopkins All Children's Hospital in St. Petersburg, Florida, and his colleagues have demonstrated an innovative new approach that shrinks group 3 medulloblastoma tumors in mice.
"Group 3 medulloblastoma is very aggressive, and there are currently no targeted therapies," says Perera, who has a primary affiliation in the Department of Neurosurgery, is a member of the Johns Hopkins Kimmel Cancer Center and is an associate professor of oncology at the Johns Hopkins University School of Medicine.
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