macrocyclic

[ mak-roh-sahy-klik, -sik-lik ]

adjective

, Chemistry.

1. having a ring structure consisting of more than 12 atoms.

Word History and Origins

Origin of macrocyclic¹

First recorded in 1945–50; macro- + cyclic

Example Sentences

The large macrocyclic structure of the catalyst allows them to catalyze even bulky ketones.

From Science Daily

In their search for a new weapon, the Roche and Harvard scientists turned their attention to a group of compounds called tethered macrocyclic peptides.

From Los Angeles Times

Hookworm is typically treated with one of three classes of antiparasitic drugs: benzimidazoles, macrocyclic lactones or tetrahydropyrimidines.

From Scientific American

PeptiDream concentrates on “constrained peptides”, particularly macrocyclic peptides - hula hoops of natural and non-natural amino acids that can carry various cargoes to specific types of cells - such as cancer or inflamed tissue.

From Reuters

To date, macrocyclic peptide drugs have shown promise in battling cancer, cardiovascular disease, inflammation and infection.

From Scientific American