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lipogenesis
/ ˌlɪpəʊˈdʒɛnɪsɪs /
noun
- biochem the synthesis of fatty acids in the body from glucose and other substrates
Example Sentences
In scientist-speak, “Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which may contribute to hyperlipidemia and obesity.”
Targeted deletion of fatty acid synthase — encoded by the Fas gene — in the gut epithelium of mice showed that epithelial de novo lipogenesis is required to maintain barrier function. -deficient epithelium has increased permeability and, as a result, increased colonic levels of proinflammatory cytokines and high serum lipopolysaccharide.
Acetate and propionate are taken up by the liver and used as substrates for lipogenesis and gluconeogenesis.
Short-chain fatty acids are absorbed in the colon, where butyrate provides energy for colonic epithelial cells, and acetate and propionate reach the liver and peripheral organs, where they are substrates for gluconeogenesis and lipogenesis.
Short-chain fatty acids are absorbed in the colon, where butyrate provides energy for colonic epithelial cells, and acetate and propionate reach the liver and peripheral organs, where they are substrates for gluconeogenesis and lipogenesis.
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