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immunological tolerance
noun
- the absence of antibody production in response to the presence of antigens, usually as a result of previous exposure to the antigens
Example Sentences
They identified an array of cell types unique to this maternal–fetal interface, and inferred the existence of a large network of potential interactions between them that would favour immunological tolerance and nurture the growth of the fetus.
However, this immunological tolerance might come at a cost.
Novakovic, B. et al. β-Glucan reverses the epigenetic state of LPS-induced immunological tolerance.
Second, abnormal microbial development during maturation of the innate immune system results in a failure to induce immunological tolerance, which then leads to exacerbated autoimmune and autoinflammatory disorders later in life.
“If you can prevent antibody formation in the first place, by finding some way of producing immunological tolerance that gets around that type of protocol, that would be a major advantage,” says David Lillicrap, a clinician and researcher who specializes in bleeding disorders at Queen's University in Kingston, Ontario, Canada.
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