imipramine

[ ih-mip-ruh-meen ]

noun

, Pharmacology.

1. a tricyclic antidepressant, C 19 H 24 N 2 , used for the symptomatic relief of depression.

imipramine

/ ɪˈmɪprəˌmiːn /

noun

1. a tricyclic antidepressant drug. Formula: C 19 H 24 N 2

Word History and Origins

Origin of imipramine¹

1955–60; contraction and rearrangement of iminodibenzyl and aminopropyl, components of the chemical name

Word History and Origins

Origin of imipramine¹

C20: from imi ( de ) + pr ( opyl ) + amine

Example Sentences

Another experimental drug, imipramine, was supposedly an antipsychotic, but scientists discovered in 1957 that it worked much better on people with depression.

From Time

Traditionalists claim that antidepressants, especially older ones such as imipramine, work only for melancholic depression.

From Washington Post

But he would be dancing at the edge of science to put suicidal patients on Prozac, while patients with melancholic depression may in fact do quite well on older agents such as imipramine.

From Washington Post

On mice with late-stage tumours that had spread throughout the brain, though, imipramine had little effect.

From Economist

The new reanalysis revealed that neither Paxil nor high-dose imipramine was more effective than a placebo in the treatment of major depression in adolescents.

From US News