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hyperkeratosis

[ hahy-per-ker-uh-toh-sis ]

noun

  1. Pathology.
    1. proliferation of the cells of the cornea.
    2. a thickening of the horny layer of the skin.
  2. Also called x-disease. Veterinary Pathology. a disease of cattle resulting from their physical contact with or eating of objects or food contaminated by wood preservatives or machinery lubricants containing highly chlorinated naphthalenes, characterized by thickening and hardening of the skin, abnormal secretion of tears and saliva, and diarrhea.


hyperkeratosis

/ ˌhaɪpəˌkɛrəˈtɒtɪk; ˌhaɪpəˌkɛrəˈtəʊsɪs /

noun

  1. pathol overgrowth and thickening of the outer layer of the skin
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Derived Forms

  • hyperkeratotic, adjective
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Other Words From

  • hy·per·ker·a·tot·ic [hahy-per-ker-, uh, -, tot, -ik], adjective
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Word History and Origins

Origin of hyperkeratosis1

From New Latin, dating back to 1835–45; hyper-, keratosis
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Example Sentences

From these samples they can diagnose a severe skin disease known as epidermolytic hyperkeratosis and such blood disorders as hemophilia and thalassemia, and the 40% of sickle cell anemia cases that amniocentesis misses.

Veterinarians at first called the sickness "Disease X," finally diagnosed it as hyperkeratosis,* a poisoning caused by chlorinated naphthalene.

An estimated 10,000 with hyperkeratosis have already gone through the yards.

In Fort Worth's stock pens, federal inspectors were carefully checking all cattle for hyperkeratosis letting them be slaughtered if not too sick.

Pathologically the first change noted in the epidermis is thought to be an acanthosis, followed by epithelial atrophy, and a hyperkeratosis, intercellular edema, and colloid degeneration of the prickle cells.

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