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hyperalgesia

[ hahy-per-al-jee-zee-uh, -see-uh ]

noun

  1. an exaggerated sense of pain ( hypalgesia ).


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Other Words From

  • hyper·al·gesic hy·per·al·get·ic [hahy-per-al-, jet, -ik], adjective
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Word History and Origins

Origin of hyperalgesia1

First recorded in 1895–1900; hyper- + algesia
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Example Sentences

Many researchers, therefore, have amelioration of hyperalgesia and allodynia foremost in their minds as they hunt for new analgesics.

He worried she was susceptible to hyperalgesia, a condition in which prolonged opioid use can alter patients’ nerve receptors and actually cause more pain.

Food and Drug Administration sent a letter to drug companies with approved opioid medications, requiring them to conduct post-marketing studies to better assess the risks of opioid side effects including opioid-induced hyperalgesia—an indication of the growing awareness surrounding this issue.

By far, the most compelling evidence for opioid-induced hyperalgesia comes from animal studies, which have shed light on potential mechanisms.

“Can you prevent opioid-induced hyperalgesia and the need for high doses by not using opioids continuously? Knowing this would help to avoid the destructive side effects seen with long-term opioid use and enable us to treat opioid patients better than we do now.”

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