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heavy chain

noun

, Immunology.
  1. either of an identical pair of Y -shaped polypeptides that, together with the light chains, constitute the antibody molecule.


heavy chain

noun

  1. immunol a type of polypeptide chain present in an immunoglobulin molecule
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

heavy chain

/ hĕvē /

  1. The larger of the two types of polypeptide chains in an immunoglobulin molecule. A heavy chain consists of an antigen-binding portion having a variable amino acid sequence, and a constant region that is different for each class of imunoglobulin. Each heavy chain is one of a Y-shaped identical pair and is attached along its variable region to a smaller light chain.
  2. Compare light chain
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Word History and Origins

Origin of heavy chain1

First recorded in 1960–65
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Example Sentences

Alberto Román Gómez captured a playful stonechat perched beside a heavy chain, resembling a tiny warrior.

From BBC

The NYPD’s deputy commissioner for public information, Tarik Sheppard, who appeared with the mayor, held up a heavy chain.

Balancing using a band and exercise ball doing pushups with a heavy chain around the neck isn’t for everyone.

He was carrying a makeshift whip with a heavy chain and padlock.

He hung a heavy chain across his driveway to keep the teens from riding their bikes up to his door.

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