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heavy chain
noun
, Immunology.
- either of an identical pair of Y -shaped polypeptides that, together with the light chains, constitute the antibody molecule.
heavy chain
noun
- immunol a type of polypeptide chain present in an immunoglobulin molecule
heavy chain
/ hĕv′ē /
- The larger of the two types of polypeptide chains in an immunoglobulin molecule. A heavy chain consists of an antigen-binding portion having a variable amino acid sequence, and a constant region that is different for each class of imunoglobulin. Each heavy chain is one of a Y-shaped identical pair and is attached along its variable region to a smaller light chain.
- Compare light chain
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Word History and Origins
Origin of heavy chain1
First recorded in 1960–65
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Example Sentences
Alberto Román Gómez captured a playful stonechat perched beside a heavy chain, resembling a tiny warrior.
From BBC
The NYPD’s deputy commissioner for public information, Tarik Sheppard, who appeared with the mayor, held up a heavy chain.
From Seattle Times
Balancing using a band and exercise ball doing pushups with a heavy chain around the neck isn’t for everyone.
From Seattle Times
He was carrying a makeshift whip with a heavy chain and padlock.
From Seattle Times
He hung a heavy chain across his driveway to keep the teens from riding their bikes up to his door.
From Los Angeles Times
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