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heavy chain
noun
- either of an identical pair of Y -shaped polypeptides that, together with the light chains, constitute the antibody molecule.
heavy chain
noun
- immunol a type of polypeptide chain present in an immunoglobulin molecule
heavy chain
/ hĕv′ē /
- The larger of the two types of polypeptide chains in an immunoglobulin molecule. A heavy chain consists of an antigen-binding portion having a variable amino acid sequence, and a constant region that is different for each class of imunoglobulin. Each heavy chain is one of a Y-shaped identical pair and is attached along its variable region to a smaller light chain.
- Compare light chain
Word History and Origins
Origin of heavy chain1
Example Sentences
He was covered in dark, full-body fur, horns curling out of his head, rattling his heavy chains at my sweet little boys.
Each master wears a heavy chain collar comprised of links of different metals, each representing a different area of study.
What was his astonishment at finding an enormous padlock and a heavy chain upon the door!
I was loaded with a heavy chain, which confined my legs, my companion the same, and we were left to our fate.
He found him sitting on the bare floor, with a heavy chain around his neck, and firmly fastened at the other end into the wall.
A house at Athens was haunted by a spirit which roamed through the apartments at night, seemingly dragging a heavy chain after it.
Their wrists were manacled, and, as a further precaution, a heavy chain bound their arms to their waists.
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