glycosylation

/ ˌɡlaɪkəʊsəˈleɪʃən /

noun

1. the process by which sugars are chemically attached to proteins to form glycoproteins

Word History and Origins

Origin of glycosylation¹

from glycosyl radical derived from glycose + -ation

Example Sentences

This sugar modification, called glycosylation, is crucial for many biological processes, including immune response.

From Science Daily

The study shows that a significant reduction of glycosylation -- a type of protein modification -- on T cell surfaces correlates with increases in CD8+ immune cells infiltrating tumors.

From Science Daily

"In B4GALT3 knockout or KO mice, we demonstrated the potential of manipulating glycosylation of the T cell surface as a new approach to cancer immunotherapy," says Heng Wei of Kyoto University's Graduate School of Medicine.

From Science Daily

Several scientists, including Srivastava, are developing open databases — such as UniCarbKB, GlyTouCan and the Glycan Mass Spectral Database — that can be used to identify sugars and common glycosylation sites on proteins.

From Nature

“You can quickly see which proteins’ glycosylation patterns are altered in cirrhosis, cancer or other diseases,” he says.

From Nature