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Gln
Example Sentences
Furthermore, each peptide has sharp bends at its Gly residues and contains two hydrophobic cores, an Asn ladder, a Gln ladder and a salt bridge between the side chain of Lys28 and the C terminus35, and its polar side chains face the solvent on the periphery of the protofilament.
If His were playing the role of Gln, it would, at least in the ground state, be required to function as a hydrogen bond acceptor and therefore be unprotonated.
Although a common mechanism with cellular GTPases may be aesthetically pleasing, it is not clear that the His in EF-Tu is directly analogous to the Gln in Ras/Ran.
Understanding the catalytic role of a Gln substitution in EF-Tu will require a more direct measurement of the catalytic rate, preferably in conjunction with a structure of the mutant complex.
The latter finding is important, because Gln cannot function as a general base.
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