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epigenomics
[ ep-i-jee-noh-miks, -nom-iks ]
noun
- Genetics. the study of epigenomes and their role in gene expression.
Word History and Origins
Origin of epigenomics1
Example Sentences
"We discovered which cell types express genes associated with schizophrenia risk differently, which biological functions are impacted within those cells, and which transcription factors are important for these changes," explained lead and co-corresponding author, W. Brad Ruzicka MD, PhD, director of the Laboratory for Epigenomics in Human Psychopathology at McLean Hospital.
"Aging neurons are an important risk factor for neurodegenerative illnesses such as Alzheimer's," says Prof. Dr. Tomohisa Toda, Professor of Neural Epigenomics at FAU and at the Max Planck Center for Physics and Medicine in Erlangen.
"Our first hint that an epigenetic clock exists in plants was revealed when we studied how DNA methylation, a chemical modification to DNA sequence underlying many epigenetic processes, varied across numerous branches in a 300-year-old poplar tree," said Frank Johannes, professor of plant epigenomics at the Technical University of Munich and co-author of the study.
Still, he says, the new study offers “a large resource for comparative epigenomics.”
It’s logical that methylation patterns track with evolution because the process itself is controlled by genes with evolving sequences, says plant epigenomics researcher Frank Johannes of the Technical University of Munich.
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