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doxorubicin

[ dok-suh-roo-buh-sin ]

noun

, Pharmacology.
  1. a cytotoxic antibiotic, C 27 H 29 NO 11 , derived from a variety of the bacterium Streptomyces peucetius and used in the treatment of sarcoma, malignant lymphoma, acute leukemia, and other cancers: administered intravenously, it is noted for its bright red color and potentially dangerous side effects.


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Word History and Origins

Origin of doxorubicin1

First recorded in 1970–75; d(e)ox(y)- + -o- + Latin rub(er) “red” (alluding to its color; rubric, red 1 ) + -i- + -(my)cin
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Example Sentences

Published in the journal Cardiovascular Research, the WSU study focused on doxorubicin, a chemotherapy drug used to treat breast cancer, lymphoma, leukemia and other cancers.

"What we're trying to do is to develop a method to locally deliver doxorubicin but also mitigate acidosis at the same time," Ahmed said.

In the new work, the Leiden team tested two anthracycline variants that remove histones without breaking DNA: an approved cancer drug called aclarubicin, and a tweaked version of doxorubicin they call diMe-Doxo.

Treatment with exosome-encased doxorubicin also shrank the tumours to a greater degree than did doxorubicin alone.

From Nature

The oncologist consulted us in cardio-oncology at Rush because there was concern her heart function would worsen with further doxorubicin treatment.

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