calcitriol

[ kal-si-tree-awl, -ol ]

noun

1. Biochemistry. a vitamin D compound, C 27 H 44 O 3 , occurring in humans as a hormone derived from cholesterol, that acts in the regulation and absorption of calcium.
2. Pharmacology. a preparation of this compound, used in the treatment of osteoporosis and bone fracture.

Word History and Origins

Origin of calcitriol¹

1975–80; apparently calci(um) + triol

Example Sentences

When needed a cell can convert calcidiol to calcitriol which is then used to turn on or turn off certain genes.

From New York Times

One may suspect that the whole point of the gene regulation by calcitriol is deliberately linked to exposure to the Sun.

From New York Times

This is then further converted into the active form of the vitamin, calcitriol, which acts as a powerful hormone. 25OHD levels in the blood are considered the best indicator of a person’s clinical vitamin D status.

From The Guardian

To make it usable by your body, your liver converts it to calcidiol, then your kidneys turn it into the active form, calcitriol.

From Seattle Times

Some studies indicate that not getting enough of this mineral may trigger the release of calcitriol, a hormone that causes the body to store fat.

From Seattle Times