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boke
/ bok; bəʊk /
verb
- to retch or vomit
noun
- a retch; vomiting fit
Word History and Origins
Origin of boke1
Example Sentences
However, "in contrast to the tens of thousands of papers on protein aggregation in neurons, how mammalian oocytes cope with protein aggregation is essentially unstudied, despite having the same problem of being long-lived and non-dividing," explains Dr. Elvan Böke, Group Leader of the Oocyte Biology & Cellular Dormancy programme at the Centre for Genomic Regulation and author of the study.
"We wanted to explore how oocytes deal with these misfolded or damaged proteins," adds Dr. Böke.
Dr. Böke's team, led by Dr. Gabriele Zaffagnini, started by collecting thousands of immature oocytes, mature eggs, and early embryos from adult mice.
"A lot of studies have historically focused on one small aspect of why oocyte quality declines, which are meiosis and euploidy. However, a recent review of eleven thousand embryo transfers has shown that the decline in female fertility with age are heavily influenced by other, yet unknown factors. Our research opens a fascinating future direction to explore whether protein degradation, and problems with how they are regulated in oocytes, could explain the age-related decline in embryo health," concludes Dr. Böke.
The country’s northwestern region of Boké, at the epicenter of the bauxite fervor, has been transformed by a relentless stream of trucks and trains hauling the precious ore along newly built roads and tracks to coastal ports.
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