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angiogenin

[ an-jee-oh-jen-in, -oj-uh-nin ]

noun

  1. a small, single-chain protein, resembling ribonuclease in structure, that stimulates the formation of new blood vessels.


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Word History and Origins

Origin of angiogenin1

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Example Sentences

By blocking angiogenin, on the other hand, doctors might not only stop the growth of tumors but perhaps prevent blindness in diabetics, a complication that results from the abnormal growth of capillaries in the retina.

A possible bonus: tests for angiogenin in the blood or urine could provide early warnings of cancer.

The protein, which the Harvard team named angiogenin, was isolated from human colon-cancer cells after a decade-long search financed by a grant from Monsanto.

Even so, says Team Member James Riordan, angiogenin is so potent that it can induce blood vessels to form when it is present in tissue as only one part per quadrillion.

While angiogenin is "cardinal to the process" of blood-vessel formation, he says, the protein is different from other known angiogenic factors that may work at different stages of the process.

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