aminopeptidase

[ uh-mee-noh-pep-ti-deys, -deyz, am-uh-noh- ]

noun

, Biochemistry.

1. any of several intestinal hydrolytic enzymes that remove an amino acid from the end of a peptide chain having a free amino group.

Word History and Origins

Origin of aminopeptidase¹

amino- + peptidase

Example Sentences

It encodes a protein called endoplasmic reticulum aminopeptidase 2, which has been shown to help immune cells recognize and fight threatening viruses.

From Science Magazine

Changes in the code for one gene stood out: ERAP2, which encodes a protein called endoplasmic reticulum aminopeptidase 2.

From Science Magazine

Zafgen’s beloranib works by inhibiting methionine aminopeptidase 2, a hormone.

From New York Times

These peptides include a close homologue of the E/S-62 leucyl aminopeptidase of the filarioid nematode Acanthocheilonema viteae, which has been shown to inhibit B-cell, T-cell and mast cell proliferation/responses, promote an alternative activation of the host macrophages, through the inhibition of the Toll-like receptor signalling pathway, and induce a Th2 response through the inhibition of IL-12p70 production by dendritic cells.

From Nature