adenosine deaminase

noun

1. an enzyme that catalyzes the conversion of adenosine to inosine and ammonia. : ADA

Example Sentences

A rare, aggressive form in children results from a mutation in a gene for a metabolic enzyme called adenosine deaminase 2.

From Scientific American

The disease at issue is severe combined immunodeficiency due to adenosine deaminase deficiency, or ADA-SCID.

From Los Angeles Times

As of last year, according to Scientific American, the FDA had approved nine gene therapies, which for the most part target rare physiological disorders, such as adenosine deaminase deficiency and lipoprotein lipase deficiency.

From Scientific American

In 2016, a drug called Strimvelis was approved in Europe for the treatment of a condition called adenosine deaminase severe combined immunodeficiency, or ADA-SCID, a form of the disease that afflicted David Vetter.

From Nature

We evolved a tRNA adenosine deaminase to operate on DNA when fused to a catalytically impaired CRISPR-Cas9.

From Nature