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retrovirus

[ re-truh-vahy-ruhs, re-truh-vahy- ]

noun

, plural ret·ro·vi·rus·es.
  1. any of a family of single-stranded RNA viruses having a helical envelope and containing an enzyme that allows for a reversal of genetic transcription, from RNA to DNA rather than the usual DNA to RNA, the newly transcribed viral DNA being incorporated into the host cell's DNA strand for the production of new RNA retroviruses: the family includes the AIDS virus and certain oncogene-carrying viruses implicated in various cancers.


retrovirus

/ ˈrɛtrəʊˌvaɪrəs /

noun

  1. any of several viruses whose genetic specification is encoded in RNA rather than DNA and that are able to reverse the normal flow of genetic information from DNA to RNA by transcribing RNA into DNA: many retroviruses are known to cause cancer in animals
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

retrovirus

/ rĕt′rō-vīrəs /

  1. Any of a group of RNA viruses whose RNA is used as a template inside a host cell for the formation of DNA by means of the enzyme reverse transcriptase. The DNA thus formed is inserted into the host cell's genome. Most retroviruses can cause cancer. Retroviruses also include HIV.

retrovirus

  1. A virus , such as HIV , whose RNA codes for DNA , which is then inserted into some part of the host's DNA. This virus comes with its own special enzyme , called reverse transcriptase, which facilitates this insertion.
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Derived Forms

  • ˈretroˌviral, adjective
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Other Words From

  • retro·viral adjective
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Word History and Origins

Origin of retrovirus1

First recorded in 1975–80; retro- + virus
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Example Sentences

The company also inactivated retroviruses that pigs carry and could be harmful to humans.

"If we didn't have retroviruses sticking their sequences into the vertebrate genome, then myelination wouldn't have happened, and without myelination, the whole diversity of vertebrates as we know it would never have happened."

However, most retrovirus integrations are very old, already degraded and therefore inactive -- their initial impact on host health has been minimised by millions of years of evolution.

"If you get infected, you've already lost the game because it's a retrovirus," Bennett agrees.

"It turned out that the antibodies are recognising remnants of what's termed endogenous retroviruses," Prof Julian Downward, an associate research director at the Francis Crick Institute, told me.

From BBC

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