Dictionary.com
Thesaurus.com
Synonyms

pestilence

American  
[pes-tl-uhns] / ˈpɛs tl əns /

noun

  1. a deadly or virulent epidemic disease.

  2. bubonic plague.

  3. something that is considered harmful, destructive, or evil.


pestilence British  
/ ˈpɛstɪləns /

noun

    1. any epidemic outbreak of a deadly and highly infectious disease, such as the plague

    2. such a disease

  1. an evil influence or idea

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • antipestilence adjective

Etymology

Origin of pestilence

First recorded in 1275–1325; Middle English, from Middle French, from Latin pestilentia, from pestilent-, stem of pestilēns “unhealthy, noxious” ( pestilent ) + -ia -y 3 ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

We can expect economic upheaval, famine and pestilence.

From The Wall Street Journal • Feb. 24, 2026

Every time she opens her mouth I swear a swarm of horseflies and pestilence are released to consume the countryside.

From Salon • Nov. 28, 2025

In dramatic lore they are known as famine, pestilence, destruction and death.

From Los Angeles Times • Nov. 2, 2024

When that happened, the gods could bring death and devastation through floods and pestilence.

From Textbooks • Apr. 19, 2023

“Those whom fire has spared are drowned by water; the man rescued from the water is saved only by air tainted with pestilence; and the survivor of war is ruined by wasting sickness.”

From "The Astonishing Life of Octavian Nothing, Traitor to the Nation, Volume II: The Kingdom on the Waves" by M.T. Anderson