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Synonyms

pestilence

American  
[pes-tl-uhns] / ˈpɛs tl əns /

noun

  1. a deadly or virulent epidemic disease.

  2. bubonic plague.

  3. something that is considered harmful, destructive, or evil.


pestilence British  
/ ˈpɛstɪləns /

noun

    1. any epidemic outbreak of a deadly and highly infectious disease, such as the plague

    2. such a disease

  1. an evil influence or idea

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of pestilence

First recorded in 1275–1325; Middle English, from Middle French, from Latin pestilentia, from pestilent-, stem of pestilēns “unhealthy, noxious” ( see pestilent) + -ia -y 3 ( def. )

Explanation

Pestilence means a deadly and overwhelming disease that affects an entire community. The Black Plague, a disease that killed over thirty percent of Europe's population, was certainly a pestilence. Pestilence is also one of the Four Horsemen of the Apocalypse in the Book of Revelation (which is part of The Bible). When pestilence rides into town, you want to be somewhere far, far away. Whereas a person gets the flu, a nation experiences a pestilence. A disease that causes widespread crop damage or animal deaths can also be called a pestilence.

Keep Reading on Vocabulary.com

Vocabulary lists containing pestilence

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Without them, we’d live in a world of putridity and pestilence.

From The Wall Street Journal Apr. 30, 2026

Invasive species came in all guises: foreign pestilence, foreign capital, and the developers.

From Slate Apr. 20, 2026

Those concepts interlace in his ossuary, enlivened when he plays his tenderly kept records, remnants of human joy all but lost to a Rage pestilence.

From Salon Jan. 23, 2026

From the Middle Ages on, Paris’ early underground waste channels were a wellspring of public fascination — and a source of pestilence, criminality and existential dread.

From Los Angeles Times Jul. 16, 2024

There was word that the pestilence crawled towards the city from the north shore, and that soon, in the alleys, we should be dying of it.

From "The Astonishing Life of Octavian Nothing, Traitor to the Nation, Volume I: The Pox Party" by M.T. Anderson

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