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Synonyms

insoluble

American  
[in-sol-yuh-buhl] / ɪnˈsɒl jə bəl /

adjective

  1. incapable of being dissolved.

    insoluble salts.

  2. incapable of being solved or explained.

    an insoluble problem.


insoluble British  
/ ɪnˈsɒljʊbəl /

adjective

  1. incapable of being dissolved; incapable of forming a solution, esp in water

  2. incapable of being solved

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

insoluble Scientific  
/ ĭn-sŏl′yə-bəl /
  1. Not capable of being fully dissolved. Fats and oils are insoluble in water.


Other Word Forms

Etymology

Origin of insoluble

1350–1400; < Latin insolūbilis; replacing Middle English insolible < Middle French insoluble < L. See in- 3, soluble

Explanation

Let a bottle of salad dressing stand on the table for a few hours and you will notice that it has separated into layers. That's because oil is insoluble or is not capable of being dissolved. Insoluble comes from the Latin insolubilis meaning "that cannot be loosened." When a substance is insoluble, it cannot be dissolved or loosened in water. Similarly, a situation that is insoluble has no hope of being solved. When a marriage is beyond repair and cannot be fixed, it is insoluble.

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Vocabulary lists containing insoluble

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

An insoluble puzzle may be how to give artificial intelligence agents complicated open-ended tasks—tasks that may have many unpredictable paths to a solution—without courting outcomes very much contrary to the intentions of the task giver.

From The Wall Street Journal ● Sep. 18, 2026

Soluble fiber dissolves in water and slows digestion, while insoluble fiber helps move waste through the digestive tract.

From Science Daily ● Mar. 8, 2026

It’s the counterpoint to Syd’s earliest argument for sticking with this insoluble endeavor: “Why can’t we put everything that we have into everything that we can?”

From Salon ● Jun. 26, 2025

In mice, the ketone ester treatment resulted in clearance rather than pathological aggregation of insoluble proteins.

From Science Daily ● Dec. 2, 2024

And now, on top of these insoluble things, her mother had only hours before probed into the pit of her soul and discovered her deep uncertainty.

From "Snow Falling on Cedars: A Novel" by David Guterson

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